Anthony Sorrentino

Mentor: Dr. Gregory Hudalla
College of Engineering
 
"I love being involved in research at the University of Florida, because I get the opportunity to work alongside talented engineers on cutting edge biotechnologies that have the potential to drastically improve healthcare."

Major

Biomedical Engineering

Minor

N/A

Research Interests

  • Protein self-assembly
  • Personalized medicine
  • Nanotechnology

Academic Awards

  • N/A

Organizations

  • Florida Blue Key
  • Student Senate
  • Engineering Student Advisory Council

Volunteer

  • University of Florida College of Dentistry
  • Project Makeover

Hobbies and Interests

  • Photography
  • Soccer
  • Hiking
  • Computer programming

Research Description

Self-Assembled Protein Heterotrimers via Charge Complementarity
My research project is to engineer a biomaterial platform based on the self- assembly of fusion proteins. This platform will enable the design of multivalent protein complexes. Applications of this platform include targeted drug delivery, medical diagnostics, and synthetic biology. The self-assembly of these fusion proteins is mediated by the formation of an alpha-helix between three complimentary peptides that have been previously shown to trimerize. This timerization is driven by charge complementarity, which prevents homotrimer formation.