Brian Nazareth

Mentor: Dr. Loic Deleyrolle
College of Medicine
 
"I got involved in research so that I could get a feeling for what a career in academia would be like, learn how to apply theoretical concepts that I have learned in practice, and learn more about a field that interests me. I am glad to be working with personalized medicine, because i feel that the field that I am involved in now will eventually be a cornerstone of cutting edge medical treatments."

Major

Biomedical Engineering

Minor

Computer Science

Research Interests

  • Personalized Nanomedicine
  • Experimental Cancer Treatments
  • Biomedical Instrumentation

Academic Awards

  • Florida Bright Futures Scholarship
  • Intel Arch Scholarship
  • University Scholars Program 2016

Organizations

  • Biomedical Engineering Society
  • Society for Biomaterials
  • Health Oriented Professional Engineering Society

Volunteer

  • Children's Cancer Center
  • Habitat for Humanity
  • Healing Horses One Child at a Time

Hobbies and Interests

  • Ultimate Frisbee
  • UF Outdoor Adventure Recreation
  • Reading (Nonfiction and Fiction)
  • Super Smash Bros

Research Description

Immune-Targeting of Slow-Cycling Malignant Glioma Cells via RNA Nanoparticle Vaccines
Glioblastoma is an agressive, malignant brain tumor and is the most common brain tumor found in humans. It is often highly resistant to conventional treatments such as chemotherapy and radiotherapy. It has been hypothesized that this is due to the effects of so called "cancerous stem cells", which have been isolated in previous experiments. This experiment aims to develop an RNA-based nanoparticle immunotherapy that can successfully incite the native immune system to identify and destroy cancerous stem cells, preventing the tumor cells' ability to proliferate in vitro.