Cooper Rickerson

Cooper Rickerson
Mentor: Dr. Sarah Glover
College of Medicine
 
"I got involved with research because it exposes me to laboratory work and gives me unique hands on experience that you cannot get in a classroom."

Major

Biomedical Engineering

Minor

N/A

Research Interests

  • Cell Signaling
  • Neural Engineering
  • Regenerative Medicine

Academic Awards

  • Gator Club Scholarship 2015
  • Dean's List 2015
  • University Scholars Program 2016

Organizations

  • Athlete Brain

Volunteer

  • Habitat for Humanity

Hobbies and Interests

  • Sports
  • Food
  • Friends

Research Description

Washing Cells Out of Scaffolding without Altering their Gene Expression Profile
Our project involves examining fibrotic gene expression levels in small bowel epithelial cells and Natural Killer (NK) cells. These two cell types are involved in the pathogenesis of fibrosis in Crohn's Disease (CD). We are aiming to engineer a series of scaffolding systems to determine the role that NK cells play in cytokine signaling and thus the fibrotic signaling cascade. Our design is to mechanically characterize, indent, tissue samples from healthy individuals and from CD patients. We will then manufacture collagen and polyacrylamide gels with different stiffnesses and seed the gels with CaCo-2 cells. My specific part of the project will be to wash the cells out of the scaffolding without altering their gene expression profile.