Miranda Schwabe


Miranda Schwabe
Mentor: Dr. Jennifer Bizon
College of Medicine
 
"I have always been passionate about science and when I began my university studies, I became curious about the brain and its complex, intricate functions. It seems that for every detail we learn about the brain there is another, more challenging question that needs to be solved. I am pursuing a career in neuroscience research because I want to help answer these questions and, in addition to satisfying my own curiosities, devote my work to answering questions about the brain that can be used to help humanity and improve society."

Major

Interdisciplinary - Neurobiological Sciences

Minor

Chemistry

Research Interests

  • Executive Function
  • Neuropharmacology
  • Neurodegeneration

Academic Awards

  • UF Presidential Service Award 2015
  • University Scholars Program 2016

Organizations

  • MentorUF
  • UF Neuroscience Club

Volunteer

  • Mentor at Gainesville High Schools
  • Brain Awareness Week
  • Florida Alternative Breaks

Hobbies and Interests

  • Cooking
  • Plants and Gardening
  • Listening to music
  • Reading

Research Description

Age-Related Changes to Metabotropic Glutamate Receptor Function in Working Memory
Age-related deficits in working memory are remarkably common, yet little is known about the specific neural changes with age that are responsible for these deficits. Glutamate is the principal excitatory neurotransmitter in the brain and has several associated receptor types that modulate the complex cortical signaling needed for cognitive function. My research project investigates metabotropic glutamate receptor (mGluR) function in the medial prefrontal cortex in a well-established rodent model of working memory. Receptor activity during a working memory task is manipulated via infusion of pharmacological agents with the goal of investigating normal mGluR contribution to working memory in young, and improving working memory function in aged cohorts.