Timothy Trinkle

Mentor: Dr. Wesley Bolch
College of Engineering
 
"I have always had a fascination with scientific processes and learning how our world and universe function - my research with CT dosimetry allows me to channel this fascination into work that can help physicians be as informed as possible about the best way to treat their patients."

Major

Nuclear and Radiological Science

Minor

N/A

Research Interests

  • CT Dosimetry
  • Computational/Physical Phantom Construction

Academic Awards

  • Anderson Scholar Award
  • Roberto Pagono Memorial Fund Recipient
  • N.I. Griesheimer Memorial Fund Recipient
  • Wunsch Scholarship Recipient

Organizations

  • Pascal's Coffeehouse

Volunteer

  • Creekside Community Church

Hobbies and Interests

  • Music
  • Tea and Coffee
  • Rock Climbing
  • Travel

Research Description

Novel Tissue-Equivalent Physical Phantoms for Experimental Validation of CT Dosimetry under TCM
The purpose of this study is to perform further physical validation for the Toshiba Aquilion ONE scanner and create TCM-specific phantoms to aid in the validation of predicting CT scanner output. These phantoms will consist of soft tissue-equivalent substitute (STES), bone tissue-equivalent substitute (BTES), lung tissue-equivalent substitute (LTES), without any air gaps in their construction. Interchangeable outer layers of adipose tissue-equivalent substitute (ATES) will be added to a single base phantom to model different weight percentiles (50%, 75% and 90%). Phantom materials and diameters will be systematically varied to closely mimic the local attenuation seen during a chest-abdomen-pelvis CT exam. Computational modeling of these phantoms will be performed in computer animation software RHINOCEROUSTM version 5.0. Production for these phantoms will require the exporting of the NURBS models created in RHINOCEROUS to a 3D-printer friendly format. Using preset molds, STES, BTES, and LTES will be synthesized and poured to assemble each phantom in sections. The major benefit to these phantoms will be their ease in computational modeling and lack of air gaps which has caused errors in the cadaver and physical phantom measurements. Once these phantoms are created, they will be used to provide a means for TCM modeling and dosimetry validation for Siemens, General Electric (GE), and Philips scanners at both UF and regional centers in Florida including Mayo Clinic – Jacksonville and Florida Hospital in Orlando. Organ doses will be assessed using optically stimulated luminescent dosimeters (OSLDs) which are calibrated according to the tube current and depth within the phantom (surface and at depth).