Mentor: Dr. Borsa and Dr. Lott
Health and Human Performance
"I have been actively involved in research since Sophomore year. I have not formally done my own project, however. I hope to gain the knowledge to create my own hypothesis, gather data, and formulate a conclusion. As a future health professional, I think it is extremely important to truly be able to understand where the research we will be studying comes from and how applicable it can be. My ultimate goal is to get published through this project."
Applied Physiology and Kinesiology
French; Health Sciences
Charles and Ethyl Mostert Scholarship (Fall 2012)
Hobbies and Interests
Does physical activity serve as a protective or injurious role for muscles in people with Collagen-6 myopathies?
Background: Collagen-6 myopathy is a congenital neuromuscular disorder that affects a wide spectrum of ages. The major complications are joint contractures, muscle weakness, and mobility. Current therapies mostly address the contracture and mobility issues through stretching and mobility aids. However, little is known about the relationship between the level of physical activity and muscle quality in this patient population. This thesis will address if a correlation exists between physical activity and muscle quality by investigating the association of physical activity with the extent of muscle pathology and strength in people with Collagen-6 myopathy. Purposes: 1) Determine the amount of physical activity, leg strength, and the muscle pathology in people with Collagen-6 myopathy compared to healthy controls. 2) Determine the relationship between physical activity, leg strength, and muscle quality in people with Collagen-6 myopathy. 3) Determine the change in physical activity, leg strength, and muscle quality in people with Collagen-6 myopathy over a one year period of time. Hypotheses: 1) The amount of physical activity, leg strength, and muscle quality will be lower in people with Collagen-6 myopathy than healthy controls 2) Leg strength and high muscle quality will be directly related to physical activity in people with Collagen-6 myopathy, 3) As leg strength and muscle quality decrease, physical activity will also decrease. Design: 1) Cross-sectional study between collagen-6 and healthy controls 2) Trends within the collagen-6 subjects