Denis Titov

Denis Titov 
Mentor: Dr. Lei Zhou
College of Medicine
 
"My interest in molecular biology was piqued when I first read about the ATPase protein in my bio class in high school. I thought the actual molecular workings of the protein were extremely interesting, and wondered whether I could do some related research when I got to UF. Turns out, molecular biology is an extremely large field and I was lucky enough to get the opportunity to join such a lab."
 

Major

Biochemistry

Minor

N/A

Research Interests

  • Aging
  • Epigenetic Control of Apoptosis
  • Development of Viable Gene Vectors into H. Sapiens

Academic Awards

  • N/A

Organizations

  • N/A

Volunteer

  • N/A

Hobbies and Interests

  • Reading
  • Exercising

Research Description

Exploring the Mechanism of Human Alpha Anti-trypsin Induced Lifespan Extension
Increasing levels of chronic inflammation and the body's reduced capacity to deal with such stress has been implicated in a number of age-related disorders, and, to a lesser degree, the aging process itself. Recently, our lab has acquired preliminary data which suggest that expression of the human Serpina1 gene in Drosophila Melanogaster hemolymph and fat body can extend the lifespan of the female fly. In addition to confirming these results, we would like to investigate whether these flies exhibit greater resistance to reactive oxygen-specie -generating agents, as well as probe the mechanism by which lifespan expansion occurs.