"I applied to the University Scholars Program because I wanted to share my research with the rest of the scientific community. Through my research, I hope to make meaningful developments in the field of cancer biology. Furthermore, I wish to expand my horizons and experience research being done in other fields that I am not so familiar with. For this academic year, I hope to finish the current research project I am working on and have it presented in a poster presentation. Additionally, I propose to work hard in all my classes, finish up the remaining classes I have for my music minor, and apply to medical school."
My primary academic and research interests are in the field of cellular and molecular biology. Currently my research is more focused on the cellular aspect of the project, but as it progresses I hope to focus more on the molecular aspects of the project.
Academic and Other Awards
- University Scholars Program Scholarship (2011-2012)
- College of Agriculture and Life Sciences Dean's List (2008-2011)
- Golden Key (2011)
- Indian Student Association
- UF ASTRA
With my club ASTRA at UF I volunteer in various places around the community such as Kids Count, where the club goes to an after school program in an underdeveloped neighborhood and spend time with the children. Furthermore, buy and cook food for the residents living at the Ronald McDonald house, Participate in the Stuff the Buss Fundraiser, and raise money for the March for Babies.
Hobbies and Interests
- Playing piano, music, music theory, computing, and technology.
Combinatorial Chemotherapy by Taxanes and Hyperthermia in Cancer Treatment
Taxanes are a group of cytotoxic drugs that includes placlitaxels and docetaxels. These drugs are powerful and most common anti-neoplastic agents for breast cancer chemotherapy and have successfully been used in clinical settings for the past 30 years. Despite this, the response rate of taxanes is only about 50%. Although the mechanisms of taxane resistance are not defined yet, resistance to taxanes have been linked to proteins involved in mitosis regulation. We suspect that introducing the cells to various lengths of heat shock will disrupt the stability of mitotic check point proteins such as cyclin B, and that stress induced by heat shock combined with taxane treatment will have a greater effect on cancer cell lines than just taxane treatment alone. In order to test the hypothesis, experiments were done to determine the appropriate amount of heat shock treatment and recovery required per cell line. Then experiments can be done to see the effectiveness of combining heat shock stress with taxane treatment. Microscopy techniques are used to analyze the status of the cancer cells and to look for indications of programmed cell death (apoptosis) or mitotic catastrophe in the form of micronucleation. From here, we can go on to analyze how heat shock plus taxane treatment affects other aspects of mitotic progression such as kinetochore-microtubule attachment as well as its interference in other mitotic checkpoint proteins. If these experiments are successful, it can lead to improved chemotherapeutical techniques and an increased effectiveness of taxane treatment in clinical settings.