Lida Esfandiary

 Lida Esfandiary
Mentor: Dr. Sabine Hediger
College of Liberal Arts and Sciences
 
"I got involved with my current research to learn new techniques and understanding about NMR and DNP-enhanced NMR on biological systems. Not only have I been able to better study molecular strucutures through the use of NMR but I have also had the opportunity to conduct my own research on resolution improvement. Moreover, I am conducting my research in France, thus allowing the opportunity to travel and learning about new cultures and lifestyles in addition to working on my project."

Major

Biology

Minor

N/A

Research Interests

  • NMR on Biological Systems
  • Medicine
  • Resolution Improvement on NMR

Academic Awards

  • UF University Scholars Program
  • Howard Hughes Medical Institute Research Award
  • UF Dean's List

Organizations

  • CHSC at UF

Volunteer

  • Noah's Endeavor
  • GSATop Soccer
  • Shand's Volunteer

Hobbies and Interests

  • Traveling
  • Hiking
  • Music
  • Reading

Research Description

Resolution Improvement in DNP-NMR Spectroscopy
The highly dynamic structure of peptidoglycan makes it a great candidate for intermolecular studies and much remains to be discovered. ssNMR combined with DNP presents itself as a technique that can be used to better understand cell-wall components and interactions. Specifically, it has been shown that the combination of high-frequency microwaves and polarizing agents, used to facilitate DNP, along with Magic Angle Spinning (MAS) techniques allows for the detection of intricate molecular structures, such as the components of bacteria cell-wall material, at much higher sensitivity. However, these techniques must still be optimized and improved to augment the study of such complicated systems. My project, therefore, is working to improve these systems by improving resolution through the use of specially applied radio frequency irradiation (pulse sequences).