Waylon Zeng

Waylon Zeng
Mentor: Dr. Lucia Notterpek
College of Medicine
 
"I have always had a great interest in how the brain and the nervous system worked. Many news articles, whether true or false, would describe mysterious functions in our nervous systems. After coming to UF, I took the initiative to investigate more on these functions. University Scholars will help me further my involvement and contribution to the laboratory as well as fuel my interest in neuroscience."

Major

Microbiology

Minor

N/A

Research Interests

  • Nervous System
  • Chemistry
  • Cell Culture

Academic Awards

  • UF University Scholars Program

Organizations

  • Tone Def A Cappella
  • AASU

Volunteer

  • Shands ER Radiology

Hobbies and Interests

  • Playing Music
  • Singing
  • DIY Projects
  • Penmanship

Research Description

Investigating the Cellular Function of PMP22 Using PMP22-deficient Fibroblasts
PMP22 is a tetraspan protein involved in the myelination of axons. Mis-expression of PMP22 is a genetic risk factor for CMT1A and other heritable neuropathies. We will be investigating the effects in PMP22-deficient mice models. Based on preliminary data from isolated PMP22-deficient Schwann cells, the absence of this gene exhibits increased proliferation and decreased migration and adhesion. We will further extend these findings and investigate potential mechanisms by which PMP22 influences motility and cell shape.